Infection:Article Title: Arthroplasties for hip fracture in adults
Article Snippet: .. Cochrane Database of Systematic Reviews ◦ WOMAC, mean: 88 Intervention group 2 (unipolar) • Age, mean: 81.4 years• Gender, M/F, n: 6/21• Additional information (scores relating to pre-injury status were obtained in the postoperative week):◦ Initial HHS, mean: 72◦ WOMAC, mean: 85 Note: • study authors did not report: BMI, medication; place of residence; comorbidities; preoperative waiting time Interventions General details: cemented Exeter femoral stem (Stryker, Kalamazoo, MI, USA); performed by consultants or registrars; postoperative 24 hour IV antibiotics, thromboprophylaxis, early mobilisation; follow-up with radiographs at first week postoperatively and at 3, 12 and 24 months Intervention group 1 • HA bipolar; Centrax head• Randomised = 24 participants (25 hips); analysed for mortality and deep infection = 24 Intervention group 2 • HA unipolar; Unitrax head• Randomised = 27; analysed for mortality and deep infection = 27 Notes: • 10 participants withdrew (unclear how these are allocated to intervention groups); 4 occurred within 3 months; a further 4 up to 2 years; 2 were not contactable• 37/51 completed 3 months; 30/51 completed 12 months; 23/51 completed 24 months Outcomes Outcomes measured/reported by study authors: HHS; WOMAC; migration of the HA head; 6MWT (available at 3, 12, and 24 months); mortality (3 months and 2 years) Outcomes relevant to the review: mortality (at 2 years); functional status (using HHS and WOMAC) and 6MWT; deep infection Notes: • we did not report HHS, 6MWT and WOMAC because these data were reported in a figure from which we could not confidently extract numerical data• we did not included mortality data at 3 months because this was reported as an overall number rather than by group Notes Funding/sponsor/declarations of interest: not reported Study dates: April 2001 and August 2003 Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk Quote: "randomly allocated to either the bipolar or unipolar group using a list with random numbers" Comment: it is unclear how the random numbers were generated Je>cote 2010 (Continued) Arthroplasties for hip fracture in adults (Review) Copyright © 2022 The Cochrane Collaboration. ..
Migration:Article Title: Arthroplasties for hip fracture in adults
Article Snippet: .. Cochrane Database of Systematic Reviews ◦ WOMAC, mean: 88 Intervention group 2 (unipolar) • Age, mean: 81.4 years• Gender, M/F, n: 6/21• Additional information (scores relating to pre-injury status were obtained in the postoperative week):◦ Initial HHS, mean: 72◦ WOMAC, mean: 85 Note: • study authors did not report: BMI, medication; place of residence; comorbidities; preoperative waiting time Interventions General details: cemented Exeter femoral stem (Stryker, Kalamazoo, MI, USA); performed by consultants or registrars; postoperative 24 hour IV antibiotics, thromboprophylaxis, early mobilisation; follow-up with radiographs at first week postoperatively and at 3, 12 and 24 months Intervention group 1 • HA bipolar; Centrax head• Randomised = 24 participants (25 hips); analysed for mortality and deep infection = 24 Intervention group 2 • HA unipolar; Unitrax head• Randomised = 27; analysed for mortality and deep infection = 27 Notes: • 10 participants withdrew (unclear how these are allocated to intervention groups); 4 occurred within 3 months; a further 4 up to 2 years; 2 were not contactable• 37/51 completed 3 months; 30/51 completed 12 months; 23/51 completed 24 months Outcomes Outcomes measured/reported by study authors: HHS; WOMAC; migration of the HA head; 6MWT (available at 3, 12, and 24 months); mortality (3 months and 2 years) Outcomes relevant to the review: mortality (at 2 years); functional status (using HHS and WOMAC) and 6MWT; deep infection Notes: • we did not report HHS, 6MWT and WOMAC because these data were reported in a figure from which we could not confidently extract numerical data• we did not included mortality data at 3 months because this was reported as an overall number rather than by group Notes Funding/sponsor/declarations of interest: not reported Study dates: April 2001 and August 2003 Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk Quote: "randomly allocated to either the bipolar or unipolar group using a list with random numbers" Comment: it is unclear how the random numbers were generated Je>cote 2010 (Continued) Arthroplasties for hip fracture in adults (Review) Copyright © 2022 The Cochrane Collaboration. ..
Article Title: Surgical interventions for treating intracapsular hip fractures in older adults: a network meta-analysis
Article Snippet: .. Cochrane Database of Systematic Reviews • Age, mean: 81.4 years• Gender, M/F, n: 6/21• Additional information (scores relating to pre-injury status were obtained in the postoperative week):◦ Initial HHS, mean: 72◦ WOMAC, mean: 85 Note: • study authors did not report: BMI, medication; place of residence; comorbidities; preoperative waiting time Interventions General details: cemented Exeter femoral stem (Stryker, Kalamazoo, MI, USA); performed by consultants or registrars; postoperative 24 hour IV antibiotics, thromboprophylaxis, early mobilisation; follow-up with radiographs at first week postoperatively and at 3, 12 and 24 months Intervention group 1 • HA bipolar; Centrax head• Randomised = 24 patients (25 hips); analysed = 24 Intervention group 2 • HA unipolar; Unitrax head• Randomised = 27; analysed = 27 Notes: • 10 participants withdrew (unclear how these were allocated to intervention groups); 4 occurred within 3 months; a further 4 up to 2 years; 2 were not contactable• 37/51 completed 3 months; 30/51 completed 12 months; 23/51 completed 24 months Outcomes Outcomes measured/reported by study authors: HHS; WOMAC; migration of the HA head; 6MWT (available at 3, 12, and 24 months); mortality (3 months and 2 years) Outcomes relevant to the review: mortality (at 2 years) Notes: • we did not included mortality data at 3 months because this was reported as an overall number rather than by group Notes Funding/sponsor/declarations of interest: not reported Study dates: April 2001 and August 2003 Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk Quote: "randomly allocated to either the bipolar or unipolar group using a list with random numbers" Comment: it is unclear how the random numbers were generated Allocation concealment (selection bias) Unclear risk Not described Blinding of participants and personnel (performance bias) All outcomes Low risk It is not possible to blind surgeons to treatment groups but we did not expect that lack of blinding would influence performance Je;cote 2010 (Continued) Surgical interventions for treating intracapsular hip fractures in older adults: a network meta-analysis (Review) Copyright © 2022 The Cochrane Collaboration. ..
Functional Assay:Article Title: Arthroplasties for hip fracture in adults
Article Snippet: .. Cochrane Database of Systematic Reviews ◦ WOMAC, mean: 88 Intervention group 2 (unipolar) • Age, mean: 81.4 years• Gender, M/F, n: 6/21• Additional information (scores relating to pre-injury status were obtained in the postoperative week):◦ Initial HHS, mean: 72◦ WOMAC, mean: 85 Note: • study authors did not report: BMI, medication; place of residence; comorbidities; preoperative waiting time Interventions General details: cemented Exeter femoral stem (Stryker, Kalamazoo, MI, USA); performed by consultants or registrars; postoperative 24 hour IV antibiotics, thromboprophylaxis, early mobilisation; follow-up with radiographs at first week postoperatively and at 3, 12 and 24 months Intervention group 1 • HA bipolar; Centrax head• Randomised = 24 participants (25 hips); analysed for mortality and deep infection = 24 Intervention group 2 • HA unipolar; Unitrax head• Randomised = 27; analysed for mortality and deep infection = 27 Notes: • 10 participants withdrew (unclear how these are allocated to intervention groups); 4 occurred within 3 months; a further 4 up to 2 years; 2 were not contactable• 37/51 completed 3 months; 30/51 completed 12 months; 23/51 completed 24 months Outcomes Outcomes measured/reported by study authors: HHS; WOMAC; migration of the HA head; 6MWT (available at 3, 12, and 24 months); mortality (3 months and 2 years) Outcomes relevant to the review: mortality (at 2 years); functional status (using HHS and WOMAC) and 6MWT; deep infection Notes: • we did not report HHS, 6MWT and WOMAC because these data were reported in a figure from which we could not confidently extract numerical data• we did not included mortality data at 3 months because this was reported as an overall number rather than by group Notes Funding/sponsor/declarations of interest: not reported Study dates: April 2001 and August 2003 Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk Quote: "randomly allocated to either the bipolar or unipolar group using a list with random numbers" Comment: it is unclear how the random numbers were generated Je>cote 2010 (Continued) Arthroplasties for hip fracture in adults (Review) Copyright © 2022 The Cochrane Collaboration. ..
Sequencing:Article Title: Arthroplasties for hip fracture in adults
Article Snippet: .. Cochrane Database of Systematic Reviews ◦ WOMAC, mean: 88 Intervention group 2 (unipolar) • Age, mean: 81.4 years• Gender, M/F, n: 6/21• Additional information (scores relating to pre-injury status were obtained in the postoperative week):◦ Initial HHS, mean: 72◦ WOMAC, mean: 85 Note: • study authors did not report: BMI, medication; place of residence; comorbidities; preoperative waiting time Interventions General details: cemented Exeter femoral stem (Stryker, Kalamazoo, MI, USA); performed by consultants or registrars; postoperative 24 hour IV antibiotics, thromboprophylaxis, early mobilisation; follow-up with radiographs at first week postoperatively and at 3, 12 and 24 months Intervention group 1 • HA bipolar; Centrax head• Randomised = 24 participants (25 hips); analysed for mortality and deep infection = 24 Intervention group 2 • HA unipolar; Unitrax head• Randomised = 27; analysed for mortality and deep infection = 27 Notes: • 10 participants withdrew (unclear how these are allocated to intervention groups); 4 occurred within 3 months; a further 4 up to 2 years; 2 were not contactable• 37/51 completed 3 months; 30/51 completed 12 months; 23/51 completed 24 months Outcomes Outcomes measured/reported by study authors: HHS; WOMAC; migration of the HA head; 6MWT (available at 3, 12, and 24 months); mortality (3 months and 2 years) Outcomes relevant to the review: mortality (at 2 years); functional status (using HHS and WOMAC) and 6MWT; deep infection Notes: • we did not report HHS, 6MWT and WOMAC because these data were reported in a figure from which we could not confidently extract numerical data• we did not included mortality data at 3 months because this was reported as an overall number rather than by group Notes Funding/sponsor/declarations of interest: not reported Study dates: April 2001 and August 2003 Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk Quote: "randomly allocated to either the bipolar or unipolar group using a list with random numbers" Comment: it is unclear how the random numbers were generated Je>cote 2010 (Continued) Arthroplasties for hip fracture in adults (Review) Copyright © 2022 The Cochrane Collaboration. ..
Article Title: Surgical interventions for treating intracapsular hip fractures in older adults: a network meta-analysis
Article Snippet: .. Cochrane Database of Systematic Reviews • Age, mean: 81.4 years• Gender, M/F, n: 6/21• Additional information (scores relating to pre-injury status were obtained in the postoperative week):◦ Initial HHS, mean: 72◦ WOMAC, mean: 85 Note: • study authors did not report: BMI, medication; place of residence; comorbidities; preoperative waiting time Interventions General details: cemented Exeter femoral stem (Stryker, Kalamazoo, MI, USA); performed by consultants or registrars; postoperative 24 hour IV antibiotics, thromboprophylaxis, early mobilisation; follow-up with radiographs at first week postoperatively and at 3, 12 and 24 months Intervention group 1 • HA bipolar; Centrax head• Randomised = 24 patients (25 hips); analysed = 24 Intervention group 2 • HA unipolar; Unitrax head• Randomised = 27; analysed = 27 Notes: • 10 participants withdrew (unclear how these were allocated to intervention groups); 4 occurred within 3 months; a further 4 up to 2 years; 2 were not contactable• 37/51 completed 3 months; 30/51 completed 12 months; 23/51 completed 24 months Outcomes Outcomes measured/reported by study authors: HHS; WOMAC; migration of the HA head; 6MWT (available at 3, 12, and 24 months); mortality (3 months and 2 years) Outcomes relevant to the review: mortality (at 2 years) Notes: • we did not included mortality data at 3 months because this was reported as an overall number rather than by group Notes Funding/sponsor/declarations of interest: not reported Study dates: April 2001 and August 2003 Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk Quote: "randomly allocated to either the bipolar or unipolar group using a list with random numbers" Comment: it is unclear how the random numbers were generated Allocation concealment (selection bias) Unclear risk Not described Blinding of participants and personnel (performance bias) All outcomes Low risk It is not possible to blind surgeons to treatment groups but we did not expect that lack of blinding would influence performance Je;cote 2010 (Continued) Surgical interventions for treating intracapsular hip fractures in older adults: a network meta-analysis (Review) Copyright © 2022 The Cochrane Collaboration. ..
Selection:Article Title: Arthroplasties for hip fracture in adults
Article Snippet: .. Cochrane Database of Systematic Reviews ◦ WOMAC, mean: 88 Intervention group 2 (unipolar) • Age, mean: 81.4 years• Gender, M/F, n: 6/21• Additional information (scores relating to pre-injury status were obtained in the postoperative week):◦ Initial HHS, mean: 72◦ WOMAC, mean: 85 Note: • study authors did not report: BMI, medication; place of residence; comorbidities; preoperative waiting time Interventions General details: cemented Exeter femoral stem (Stryker, Kalamazoo, MI, USA); performed by consultants or registrars; postoperative 24 hour IV antibiotics, thromboprophylaxis, early mobilisation; follow-up with radiographs at first week postoperatively and at 3, 12 and 24 months Intervention group 1 • HA bipolar; Centrax head• Randomised = 24 participants (25 hips); analysed for mortality and deep infection = 24 Intervention group 2 • HA unipolar; Unitrax head• Randomised = 27; analysed for mortality and deep infection = 27 Notes: • 10 participants withdrew (unclear how these are allocated to intervention groups); 4 occurred within 3 months; a further 4 up to 2 years; 2 were not contactable• 37/51 completed 3 months; 30/51 completed 12 months; 23/51 completed 24 months Outcomes Outcomes measured/reported by study authors: HHS; WOMAC; migration of the HA head; 6MWT (available at 3, 12, and 24 months); mortality (3 months and 2 years) Outcomes relevant to the review: mortality (at 2 years); functional status (using HHS and WOMAC) and 6MWT; deep infection Notes: • we did not report HHS, 6MWT and WOMAC because these data were reported in a figure from which we could not confidently extract numerical data• we did not included mortality data at 3 months because this was reported as an overall number rather than by group Notes Funding/sponsor/declarations of interest: not reported Study dates: April 2001 and August 2003 Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk Quote: "randomly allocated to either the bipolar or unipolar group using a list with random numbers" Comment: it is unclear how the random numbers were generated Je>cote 2010 (Continued) Arthroplasties for hip fracture in adults (Review) Copyright © 2022 The Cochrane Collaboration. ..
Article Title: Surgical interventions for treating intracapsular hip fractures in older adults: a network meta-analysis
Article Snippet: .. Cochrane Database of Systematic Reviews • Age, mean: 81.4 years• Gender, M/F, n: 6/21• Additional information (scores relating to pre-injury status were obtained in the postoperative week):◦ Initial HHS, mean: 72◦ WOMAC, mean: 85 Note: • study authors did not report: BMI, medication; place of residence; comorbidities; preoperative waiting time Interventions General details: cemented Exeter femoral stem (Stryker, Kalamazoo, MI, USA); performed by consultants or registrars; postoperative 24 hour IV antibiotics, thromboprophylaxis, early mobilisation; follow-up with radiographs at first week postoperatively and at 3, 12 and 24 months Intervention group 1 • HA bipolar; Centrax head• Randomised = 24 patients (25 hips); analysed = 24 Intervention group 2 • HA unipolar; Unitrax head• Randomised = 27; analysed = 27 Notes: • 10 participants withdrew (unclear how these were allocated to intervention groups); 4 occurred within 3 months; a further 4 up to 2 years; 2 were not contactable• 37/51 completed 3 months; 30/51 completed 12 months; 23/51 completed 24 months Outcomes Outcomes measured/reported by study authors: HHS; WOMAC; migration of the HA head; 6MWT (available at 3, 12, and 24 months); mortality (3 months and 2 years) Outcomes relevant to the review: mortality (at 2 years) Notes: • we did not included mortality data at 3 months because this was reported as an overall number rather than by group Notes Funding/sponsor/declarations of interest: not reported Study dates: April 2001 and August 2003 Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk Quote: "randomly allocated to either the bipolar or unipolar group using a list with random numbers" Comment: it is unclear how the random numbers were generated Allocation concealment (selection bias) Unclear risk Not described Blinding of participants and personnel (performance bias) All outcomes Low risk It is not possible to blind surgeons to treatment groups but we did not expect that lack of blinding would influence performance Je;cote 2010 (Continued) Surgical interventions for treating intracapsular hip fractures in older adults: a network meta-analysis (Review) Copyright © 2022 The Cochrane Collaboration. ..
Generated:Article Title: Arthroplasties for hip fracture in adults
Article Snippet: .. Cochrane Database of Systematic Reviews ◦ WOMAC, mean: 88 Intervention group 2 (unipolar) • Age, mean: 81.4 years• Gender, M/F, n: 6/21• Additional information (scores relating to pre-injury status were obtained in the postoperative week):◦ Initial HHS, mean: 72◦ WOMAC, mean: 85 Note: • study authors did not report: BMI, medication; place of residence; comorbidities; preoperative waiting time Interventions General details: cemented Exeter femoral stem (Stryker, Kalamazoo, MI, USA); performed by consultants or registrars; postoperative 24 hour IV antibiotics, thromboprophylaxis, early mobilisation; follow-up with radiographs at first week postoperatively and at 3, 12 and 24 months Intervention group 1 • HA bipolar; Centrax head• Randomised = 24 participants (25 hips); analysed for mortality and deep infection = 24 Intervention group 2 • HA unipolar; Unitrax head• Randomised = 27; analysed for mortality and deep infection = 27 Notes: • 10 participants withdrew (unclear how these are allocated to intervention groups); 4 occurred within 3 months; a further 4 up to 2 years; 2 were not contactable• 37/51 completed 3 months; 30/51 completed 12 months; 23/51 completed 24 months Outcomes Outcomes measured/reported by study authors: HHS; WOMAC; migration of the HA head; 6MWT (available at 3, 12, and 24 months); mortality (3 months and 2 years) Outcomes relevant to the review: mortality (at 2 years); functional status (using HHS and WOMAC) and 6MWT; deep infection Notes: • we did not report HHS, 6MWT and WOMAC because these data were reported in a figure from which we could not confidently extract numerical data• we did not included mortality data at 3 months because this was reported as an overall number rather than by group Notes Funding/sponsor/declarations of interest: not reported Study dates: April 2001 and August 2003 Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk Quote: "randomly allocated to either the bipolar or unipolar group using a list with random numbers" Comment: it is unclear how the random numbers were generated Je>cote 2010 (Continued) Arthroplasties for hip fracture in adults (Review) Copyright © 2022 The Cochrane Collaboration. ..
Article Title: Surgical interventions for treating intracapsular hip fractures in older adults: a network meta-analysis
Article Snippet: .. Cochrane Database of Systematic Reviews • Age, mean: 81.4 years• Gender, M/F, n: 6/21• Additional information (scores relating to pre-injury status were obtained in the postoperative week):◦ Initial HHS, mean: 72◦ WOMAC, mean: 85 Note: • study authors did not report: BMI, medication; place of residence; comorbidities; preoperative waiting time Interventions General details: cemented Exeter femoral stem (Stryker, Kalamazoo, MI, USA); performed by consultants or registrars; postoperative 24 hour IV antibiotics, thromboprophylaxis, early mobilisation; follow-up with radiographs at first week postoperatively and at 3, 12 and 24 months Intervention group 1 • HA bipolar; Centrax head• Randomised = 24 patients (25 hips); analysed = 24 Intervention group 2 • HA unipolar; Unitrax head• Randomised = 27; analysed = 27 Notes: • 10 participants withdrew (unclear how these were allocated to intervention groups); 4 occurred within 3 months; a further 4 up to 2 years; 2 were not contactable• 37/51 completed 3 months; 30/51 completed 12 months; 23/51 completed 24 months Outcomes Outcomes measured/reported by study authors: HHS; WOMAC; migration of the HA head; 6MWT (available at 3, 12, and 24 months); mortality (3 months and 2 years) Outcomes relevant to the review: mortality (at 2 years) Notes: • we did not included mortality data at 3 months because this was reported as an overall number rather than by group Notes Funding/sponsor/declarations of interest: not reported Study dates: April 2001 and August 2003 Risk of bias Bias Authors' judgement Support for judgement Random sequence generation (selection bias) Unclear risk Quote: "randomly allocated to either the bipolar or unipolar group using a list with random numbers" Comment: it is unclear how the random numbers were generated Allocation concealment (selection bias) Unclear risk Not described Blinding of participants and personnel (performance bias) All outcomes Low risk It is not possible to blind surgeons to treatment groups but we did not expect that lack of blinding would influence performance Je;cote 2010 (Continued) Surgical interventions for treating intracapsular hip fractures in older adults: a network meta-analysis (Review) Copyright © 2022 The Cochrane Collaboration. ..
other:Article Title: Functional outcome of debridement, antibiotics and implant retention in periprosthetic joint infection involving the hip
Article Snippet: G. Grammatopoulos, DPhil, FRCS (Tr&Orth), Fellow M-E. Bolduc, MD, Fellow B. L. Atkins, MBBS, MSc, FRCP, FRCPath, Consultant in Infectious Diseases and Microbiology B. J. L. Kendrick, DPhil, FRCS (Tr&Orth), Consultant Orthopaedic Surgeon P. McLardy-Smith, FRCS, Consultant Orthopaedic Surgeon D. W. Murray, MD, FRCS, Consultant Orthopaedic Surgeon R. Gundle, DPhil, FRCS, Consultant Orthopaedic Surgeon A. H. Taylor, FRCS (Tr&Orth), Consultant Orthopaedic Surgeon Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford, OX3 7HE, UK.
Comparison:Article Title: Still no single gold standard for using cementless femoral stems routinely in total hip arthroplasty
Article Snippet: .. Both the RIPO and the National Joint Registry reports provide limited information that allows comparison of risk of failure for implant designs; the most popular constructs are the cementless Corail femoral stem and Pinnacle acetabular cup (DePuy, Warsaw, IN), the cemented Exeter femoral stem, and Contemporary acetabular cup (Stryker, Kalamazoo, MI), and the hybrid construct with the cemented Exeter femoral stem and the cementless Trident cup (Stryker, Kalamazoo, MI). ..
Construct:Article Title: Still no single gold standard for using cementless femoral stems routinely in total hip arthroplasty
Article Snippet: .. Both the RIPO and the National Joint Registry reports provide limited information that allows comparison of risk of failure for implant designs; the most popular constructs are the cementless Corail femoral stem and Pinnacle acetabular cup (DePuy, Warsaw, IN), the cemented Exeter femoral stem, and Contemporary acetabular cup (Stryker, Kalamazoo, MI), and the hybrid construct with the cemented Exeter femoral stem and the cementless Trident cup (Stryker, Kalamazoo, MI). ..
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